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Please use this identifier to cite or link to this item: http://hdl.handle.net/1834/963

Title: Clionasterol, a Triterpenoid from the Kenyan Marine Green Macroalga Halimeda macroloba
Authors: Jaspars, M.
Dzeha, T.
Tabudravu, J.
ASFA Terms: Algae
Issue Date: 2003
Publisher: WIOMSA
Citation: Western Indian Ocean J. Mar. Sci., 2 (2), p. 157-161
Abstract: The triterpenoid clionasterol (1), a 29 carbon structure compound was isolated from the less polar extract (20% EtOAc in hexanes) of the green alga Halimeda macroloba collected at Shimoni near Mombasa, Kenya. The structure and relative stereochemistry of this compound was elucidated by spectroscopic data, mainly NMR and mass spectrometry. This metabolite was inactive against DLD-1 cells on the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. Further experiments on mosquito larvae and brine shrimp lethality confirmed this result.
URI: http://hdl.handle.net/1834/963
ISSN: 0856-860X
Appears in Collections:Miscellaneous
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