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http://hdl.handle.net/1834/963
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| Title: | Clionasterol, a Triterpenoid from the Kenyan Marine Green Macroalga Halimeda macroloba |
| Authors: | Jaspars, M.
Dzeha, T.
Tabudravu, J. |
| ASFA Terms: | Algae |
| Issue Date: | 2003 |
| Publisher: | WIOMSA |
| Citation: | Western Indian Ocean J. Mar. Sci., 2 (2), p. 157-161 |
| Abstract: | The triterpenoid clionasterol (1), a 29 carbon structure compound was isolated from
the less polar extract (20% EtOAc in hexanes) of the green alga Halimeda macroloba collected
at Shimoni near Mombasa, Kenya. The structure and relative stereochemistry of this compound
was elucidated by spectroscopic data, mainly NMR and mass spectrometry. This metabolite
was inactive against DLD-1 cells on the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium
bromide) assay. Further experiments on mosquito larvae and brine shrimp lethality confirmed this result. |
| URI: | http://hdl.handle.net/1834/963 |
| ISSN: | 0856-860X |
| Appears in Collections: | Miscellaneous
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