|
OceanDocs >
Latin America >
CUBA >
Centro de Bioproductos Marinos >
1. Articulos científicos >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/1834/3860
|
| Title: | Polar Alkaloids from the Caribbean Marine Sponge Niphates digitalis |
| Authors: | Regalado, E.L.
Mendiola, J.
Laguna, A.
Nogueiras, C.
Thomas, O.P. |
| ASFA Terms: | Sponges
Cytotoxicity |
| Issue Date: | 2010 |
| Citation: | Natural Produts Communications, 5(8). p. 1187-1190 |
| Abstract: | A method involving flash chromatography, semi-preparative phenylhexyl RP HPLC-DAD-ELSD combined with analytic
polar-RP HPLC-DAD, was applied to separate and purify six highly nitrogenated bases and a bicyclic amidine alkaloid, the
major components of the marine sponge Niphates digitalis. Their structures were identified as 1,8-diazabicyclo[5.4.0]undec-7-
ene (1), deoxycytidine (2), phenylalanine (3), adenosine (4), deoxyguanosine (5), adenine (6) and thymidine (7) on the basis of
spectroscopic data analyses. This is the first report of these compounds in a marine sponge belonging to the Niphates genus and
the first evidence of the presence of 1 from a natural source. |
| URI: | http://hdl.handle.net/1834/3860 |
| Related document: | http://pubget.com/paper/20839615 |
| Appears in Collections: | 1. Articulos científicos
|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
|
